Predicting drug metabolism: Concepts and challenges
نویسندگان
چکیده
منابع مشابه
Predicting drug metabolism: Concepts and challenges*
The paper begins with a discussion of the needs and goals of metabolic predictions in early drug research. Major difficulties toward this objective are examined, mainly the various substrate and product selectivities characteristic of drug metabolism. In a second part, we classify and summarize the major in silico methods used to predict drug metabolism. A discrimination is thus made between “l...
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ژورنال
عنوان ژورنال: Pure and Applied Chemistry
سال: 2004
ISSN: 1365-3075,0033-4545
DOI: 10.1351/pac200476050907